Words similar to neurotrophins

Example sentences for: neurotrophins

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The progressive loss of afferent and efferent innervation in Brn3c null mutants shows neither in spatial nor in temporal pattern a resemblance to losses reported in simple BDNF or NT-3 null mutations [ 6 ] . Null mutants of ear specific neurotrophins have completed the loss of sensory neurons before birth.
However, known neurotrophins are largely absent in the adult cochleae [ 4 ] and significant amounts of neurotrophin expression appear to develop only in postnatal animals in the CNS [ 24 ] . Such expression in the CNS could possibly offset to some extent the peripheral loss of neutrophins in targeted null mutants.
Long term survival of apical sensory neurons is unrelated to differentiated hair cells and likely is independent of neurotrophins
Despite this reduction, some, apparently biologically significant low levels of neurotrophins are apparently expressed in all sensory epithelia in embryonic Brn3c null mutants.
NT-3 is the most abundantly expressed of the three neurotrophins during embryonic muscle development, followed by NT-4/5 and BDNF [ 1 2 ] . After birth, NT-3 and NT-4/5 are down-regulated in muscle whereas BDNF continues to be expressed at low levels [ 1 ] . BDNF mRNA is expressed in myocytes in the adult muscle [ 3 ] . Essentially nothing is known about BDNF gene expression in fish muscle.