Words similar to neurotrophic
Example sentences for: neurotrophic
How can you use “neurotrophic” in a sentence? Here are some example sentences to help you improve your vocabulary:
.. ", ultimately leading to " ...expression of brain-derived neurotrophic factor (BDNF) messenger RNA " in cerebellar primary culture neurons [ 56 ] . In another study, basic fibroblast growth factor (bFGF) was shown to significantly protect cerebellar granule neurons in culture from the neurotoxicity by domoic acid, perhaps " ...through a direct interaction of bFGF and bFGF receptors on the neuronal surface.
In the PEDF spatial structure, the putative GAG binding domain is distinct from and non-overlapping with the neurotrophic active region [ 14 20 ] .
It induces neuronal differentiation in retinoblastoma cells, protects retina neurons (including photoreceptors) from death by apoptosis and other insults, and has a morphogenetic effect on photoreceptor cells [ 3 4 5 6 ] . It also has neurotrophic effects on neurons from the cerebellum, hippocampus and spinal cord [ 7 8 9 10 11 12 ] . In the intact retina, this factor is identified as a secreted protein associated by ionic interactions with the interphotoreceptor matrix [ 13 14 ] , where GAGs are the major polyanionic components.
Although details of the mechanism remain to be revealed, it is clear that heparin/HS is required for the first step of the neurotrophic activity of PEDF, namely the encounters with its receptor at the cell surface.
Specifically, efferent fibers may suffer the same loss of their molecularly unknown neurotrophic support as do afferents and therefore show the same spatio-temporal profile of loss (Fig.