Words similar to neurotoxicity

Example sentences for: neurotoxicity

How can you use “neurotoxicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus, mefloquine apparently crosses the blood-brain barrier and accumulates to sufficient levels to include those concentrations found to disrupt neuronal calcium homeostasis and ER function in vitro . The possibility that a disruption of neuronal calcium homeostasis or ER function may be responsible, at least in part, for the clinical neurotoxicity of mefloquine is worthy of further investigation.
Blocking of neurotoxicity of supernatants from HIV infected monocytes with antisera to gp120 and Tat
In the present study, utilizing confocal microscopy and Affymetrix arrays, we have shown that at least one component of the neurotoxicity of mefloquine can be attributed to an effect on the ER calcium store, and that the drug activates a UPR similar to that induced by agents known to disrupt ER function.
Firstly, the trigger for the sustained elevation in cytoplasmic calcium may occur at the level of the ER, and secondly, this effect may also contribute substantially to the neurotoxicity of mefloquine.
Effect of lower mefloquine concentrations on ER calcium homeostasis and relationship to time-dependent neurotoxicity