Words similar to neurotoxicity
Example sentences for: neurotoxicity
How can you use “neurotoxicity” in a sentence? Here are some example sentences to help you improve your vocabulary:
A hyper-responsiveness of AKXD28 ocular tissues to PAF or increased activity of the PTAFR receptor mediated signaling pathway could, therefore, contribute to the pronounced retinal damage through potentiating glutamate neurotoxicity.
Acting through N-methyl-D-aspartate receptors, glutamate is believed to be a potent initiator of RGC neurotoxicity [ 26] and, as described here, the vitreous of at least some AKXD28 mice contains elevated glutamate concentrations when IOP is elevated.
The effects were observed at physiologically relevant concentrations and may contribute to the acute neurotoxicity of the drug in vitro .
.. ", ultimately leading to " ...expression of brain-derived neurotrophic factor (BDNF) messenger RNA " in cerebellar primary culture neurons [ 56 ] . In another study, basic fibroblast growth factor (bFGF) was shown to significantly protect cerebellar granule neurons in culture from the neurotoxicity by domoic acid, perhaps " ...through a direct interaction of bFGF and bFGF receptors on the neuronal surface.
Although these findings are promising and implicate glutamate in retinal neurotoxicity in AKXD28 mice, further experiments are needed to completely characterize vitreous glutamate levels and their relationship to IOP and glaucoma in this strain.