Example sentences for: neurotrophin

How can you use “neurotrophin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, all of the neurotrophin/neurotrophin receptor null mutants studied to date eliminate expression in both the peripheral target and the brain simultaneously and achieve their effects in late embryos.

  • We processed four ears of P0 and P8 Brn3c null and control littermates for expression of BDNF and NT-3 using the riboprobes previously described [ 7 ] . We did not analyze neurotrophin expression in 6-month old animals as neurotrophins are downregulated in neonates [ 20 ] and no expression can be found even in normal animals [ 4 ] . In the canal cristae we expected, and found, only a BDNF signal.

  • The ligands ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and a novel neurotrophin set, known alternatively as NNT-1/BSF3 and CLF/CLC, also function through the high affinity LIFR:gp130 heterodimeric receptor but require a third ligand-binding but non-signaling subunit [ 1 2 3 4 ] . Oncostatin M (OSM) utilizes LIFR:gp130 as an alternative receptor complex for OSM signaling in humans [ 5 ] , but not in mice [ 6 ] . Thus, in mice LIFR:gp130 is obligatory for signaling induced by LIF, CNTF, CT-1 and CLF/CLC.

  • However, there is one qualitative difference not recognized in any single neurotrophin null mutant.

  • In situhybridization confirms neonatal neurotrophin expression


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