Words similar to neut
Example sentences for: neut
How can you use “neut” in a sentence? Here are some example sentences to help you improve your vocabulary:
The first method, M1, uses the information contained in both x neut ( d ) and x comp ( d ). As explained below, this method tends to overestimate the contribution of w comp ( d ). Let γ ( d ) = w neut ( d )/ [ w neut ( d ) + w comp ( d )], which is the fraction of viable sequences belonging to the reference neutral network at distance d . Then, w neut ( d ) is simply given by
This double counting means that our methods have the tendency to overestimate w neut ( d ). This overestimation, however, is not problematic in the context of the present paper, because - as we emphasized in the results - our main conclusions are based on the large contribution of w comp ( d ) to w ( d ). A correction for the overestimation of w neut ( d ) would increase the contribution of w comp ( d ), and would therefore make our conclusions even stronger.
This contribution is given by [1 - γ ( d )] w ( d ) x neut ( d ). We must then obtain the contribution of additional compensatory mutations at distance d + 1. These are given by 1 - w ( d ), the number of non-viable sequences at distance d , multiplied by the probability with which these non-viables turn into viable sequences after a single mutation, x comp ( d ). Hence, we arrive at
For w ( d ), average <β> = 0.893 ± 0.006 (standard error of the mean), while for w neut ( d ) the average <β> = 0.983 ± 0.004 by M2 or 1.046 ± 0.005 by M1.
In this case, the quantity x comp ( d ) drops out, which insures that w neut ( d ) + w comp ( d ) is always identical to w ( d ). M2 does not suffer from double counting viable sequences, but it uses less information than M1 and depends on an additional assumption.
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