Example sentences for: mglur

How can you use “mglur” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Still, it appears likely that Siah1a may play an important role in mGluR signaling in addition to any putative function regarding the proteasome pathway.

  • Further, a mutant of Siah1a was constructed with the RING finger domain deleted, such that the protein was unable to act in the ubiquitin/proteasome pathway [ 46 ] . This deletion construct was as effective in attenuating group I mGluR function as the wild type Siah1a, providing supporting evidence that the effect of Siah1a resulted from its physical association with the receptors, rather than through a resulting reduction in receptor expression levels.

  • The subcellular distribution of mGluR1a-GFP was also examined with and without Siah1a.

  • The strong reduction in calcium current modulation by glutamate in the presence of Siah1a was observed with every group I mGluR tested.

  • In cells expressing mGluR5a and GFP-Siah1a-CT, inhibition was reduced to 14 ± 3 (n = 6; p < 0.05; figure 5B).


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