Words similar to mglur
Example sentences for: mglur
How can you use “mglur” in a sentence? Here are some example sentences to help you improve your vocabulary:
The strong reduction in calcium current modulation by glutamate in the presence of Siah1a was observed with every group I mGluR tested.
These data also suggest that Siah1a is acting at the level of the receptor, since much of the calcium current modulation through group I mGluRs proceeds through a Gβγ-mediated pathway similar to that used by α 2 adrenergic receptors and mGluR2 [ 38 40 ] .
Consistent with previous reports [ 24 38 ] , calcium current inhibition via mGluR5b appeared partially voltage dependent.
These proteins have been implicated in many processes including cancer [ 33 ] , apoptosis [ 34 ] and cell cycle regulation [ 35 ] . More recently, an interaction between Siah1a and the C-terminal tail of group I mGluRs was demonstrated [ 36 ] . This interaction was specific for group I mGluRs, as it was not observed in the analogous sequences from group II (mGluR2) or group III (mGluR7) receptors.
The latter hypothesis predicts a reduction in mGluR cell surface expression or perhaps a change in surface distribution in the presence of Siah1a, such as occurs in the presence of Homer proteins [ 24 44 45 ] . To test whether Siah1a expression altered the surface expression of group I mGluRs, the surface distribution of mGluR5a-myc was examined in the absence and presence of Siah1a.
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