Example sentences for: mcul

How can you use “mcul” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The reciprocal suppression by E2F mutation and enhancement by E2F overexpression show that the apoptosis triggered by mCul1 is mediated by or requires E2F function.

  • The experiments described above demonstrate that overexpression of mCul1 produces a phenotype that can be modified by second site mutations and therefore could be used for a more general genome-wide modifier-screen.

  • The small wing phenotype seen in flies overexpressing mCul1 was enhanced when flies also had a deficiency uncovering this region (fig.

  • These data show that overexpression of mouse Cul1 has a dominant negative effect on Cul1 function, or that dCul1 suppresses a neomorphic activity of mCul1 .

  • While the basis for the dominant negative effect of mCul1 remains unknown, it is important to recognize that inactivation of the endogenous Cul1 is incomplete so that a reduced level of Cul1 activity persists.


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