Words similar to mglurs

Example sentences for: mglurs

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For example, binding of Siah1a to the C-terminus of group I mGluRs may occlude the region or regions responsible for G protein activation.
Phosphorylation of the receptors at specific sites prevents CaM binding to mGluRs [ 25 ] . Association of Siah1a with group I mGluRs can also prevent the interaction of CaM and the receptor [ 36 ] . This competition for binding was predicted due to the overlap in binding sites on the C-terminal tail for CaM and Siah1a [ 36 ] . Although CaM has been known to associate with group I mGluRs for some time, the functional role of this interaction is unknown.
Calcium current inhibition in cells expressing the group I mGluR, mGluR5b was 29 ± 2% (figure 6; n = 21), similar to that through other group I mGluRs tested (see figure 2).
To examine the role of Siah1a expression on mGluR function, SCG neurons were injected with cDNA encoding several group I mGluRs (mGluR1, 5 and their splice variants) with or without Siah1a expression.
Finally, CaM binding to the mGluRs did not appear to be Ca 2+-dependent.