Words similar to mglurs

Example sentences for: mglurs

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However, CaM can also interact with group III mGluRs [ 26 28 ] . Recent data suggests that the association of CaM with group III mGluRs is necessary for normal G protein activation [ 27 ] . By analogy to group III mGluRs, the ability of Siah1a to compete with CaM for binding to group I mGluRs was considered a potential mechanism for the actions of Siah1a on group I mGluR-mediated calcium current inhibition.
The data imply two possible mechanisms for the effect of Siah1a on mGluR signaling: First, CaM association with group I mGluRs increases G protein coupling (or perhaps is required, as may be the case with group III mGluRs).
Coexpression of Siah1a with group I mGluRs
Calmodulin (CaM), a calcium binding protein intricately involved in intracellular signaling, interacts with the C-terminal tail of group I mGluRs [ 25 ] . This interaction appears to be dynamically regulated.
This reduction of modulation by glutamate appeared to be specific for mGluRs, as NE-mediated calcium current inhibition was unaltered (figure ID).