Words similar to methylated
Example sentences for: methylated
How can you use “methylated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cox Proportional Hazard Models [ 57 ] were further applied to assess the relative hazard (risk) of dying associated with each methylated gene after adjusting for age, treatment status, tumor size, stage, and HPV type.
The promoters of CDKN2A , MGMT , BRCA1 , TP73 , TIMP3 , GSTP1 , and MLH1 genes were rarely (<10% cases) methylated.
Of the six cell lines with RARB gene methylated, three (HT-3, MS751, and ME-180) exhibited reactivation upon treatment with 5-Aza-2' deoxycytidine or n-butyrate alone or the combination of the two.
By performing PCR amplification across this region after cutting with the methylation-sensitive enzyme Hpa II, the relative amounts of the methylated AR alleles can be quantitatively determined with a high degree of accuracy; variance on repeated assays is approximately 4% [ 12].
The primers used for amplification of methylated and unmethylated promoters of genes RARB , TIMP3 , CDKN2A , p14 ARF , MGMT , DAPK , CDH1 , GSTP1 , APC promoter 1A, RB1 , MLH1 , TP73 , BRCA1 , FHIT , and HIC1 have been described previously http://pathology2.jhu.edu/pancreas/prim0425.htm#MSP; [ 32 47 48 49 ] . Methylated (MF and MR) and unmethylated (UF and UR) primers for RASSF1A promoter were designed according to Herman et al [ 46 ] and as described earlier [ 50 ] . PCR products were run on 2% agarose gels and visualized after ethidium bromide staining.
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