Example sentences for: methylated

How can you use “methylated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Of these, 15 genes ( MGMT , RASSF1A , APC , RARB , CDH1 , MLH1 , TIMP3 , GSTP1 , DAPK , CDKN2A , p14 ARF , BRCA1 , FHIT , TP73 , and HIC1 ) had previously been shown to be commonly methylated in various solid tumor types [ 4 ] . Six additional genes ( RB1 , NME1 , NME2 , BTG1 , NEDD1 , and APAF1 ) were studied because of their possible involvement in genetic alterations in GCT as indicated by LOH studies [ 8 9 10 ] . The RB1 gene at 13q14.

  • The RASSF1A gene was methylated in 3 of the 5 cell lines studied.

  • CDH1, DAPK, RARB and HIC1 gene promoters are frequently methylated in CC

  • Dong and co-workers have shown earlier that the CDH1 promoter is methylated in 28% of invasive CC [ 13 ] . E-cadherin, CDH1 , is a major adhesion component of epithelial cells, which plays an important role as an invasion suppressor gene.

  • Cox Proportional Hazard Models [ 57 ] were further applied to assess the relative hazard (risk) of dying associated with each methylated gene after adjusting for age, treatment status, tumor size, stage, and HPV type.


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