Example sentences for: methylphenidate

How can you use “methylphenidate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is not just technophobes who wonder whether a society that consumes 90% of the world's supply of methylphenidate (Ritalin), where the most profitable class of drugs is antidepressants, and where cosmetic surgeons perform liposuction on prime-time television is a society that has somehow lost its way.

  • The psychostimulants (eg, methylphenidate) may also be effective [ 73 ] .

  • When reversal of depression is an immediate short-term goal, a rapid-acting psychostimulant (such as methylphenidate) is the best choice [ 38 ] . If a response in 2 to 4 weeks is acceptable, an atypical antidepressant or selective serotonin reuptake inhibitor (SSRI) may be an appropriate choice [ 39 ] . Tricyclic antidepressants have limited usefulness due to their long time to achieve therapeutic levels and risk of anticholinergic adverse effects [ 40 ] . If the diagnosis is unclear, or the expected therapeutic response delayed, consult with a colleague with expertise.

  • 3 [ 43 ] . Methylphenidate, the primary stimulant used in pharmacological treatment of ADHD, was shown by PET imaging to block the dopamine transporter [ 44 ] . ADHD patients have also been found to show higher levels of DAT1 in the striatum [ 45 ] . The most well studied polymorphism is a VNTR in the 3' untranslated region of the DAT gene [ 46 ] . Since this VNTR is not in the coding region of the DAT gene, it does not affect the protein sequence of the dopamine transporter, but may affect the translational efficiency and thus the amount of protein expressed.


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