Example sentences for: membrane-spanning

How can you use “membrane-spanning” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The TMC protein family has eight members in vertebrates and forms three subfamilies, A, B, and C. TMCs are proteins with a conserved core of eight membrane-spanning domains.

  • On the basis of comparative structural predictions of all mammalian TMCs we propose a basic topology of the generic TMC protein with variable intracellular amino- and carboxyl-termini, a conserved core with eight membrane-spanning domains, and some variability in the length of several intra- and extracellular loops (Figure 2).

  • Molecular modeling suggested that this 'retention' motif - ExxHxR in the first and ExxNxR in the third membrane-spanning region - within all LHCPs and related proteins provides two ligands for Chl, an ion-pair between Glu (E) and Arg (R) and the sidechain of either His (H) or Asn (N).

  • Thus, all GOLD-domain proteins can be divided into two architectural categories: the p24-like category, in which the GOLD domains project into the lumen, anchored in the membrane by the membrane-spanning helix (category 1); and proteins in which the GOLD domain occurs at the extreme amino or carboxyl terminus, with additional domains that are known to interact with lipid membranes (category 2) (Figure 2).

  • The VR1 channel is a member of the superfamily of ion channels with six membrane-spanning domains, with highest homology to the trp family of ion channels.


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