Example sentences for: membrane-spanning

How can you use “membrane-spanning” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • On the basis of comparative structural predictions of all mammalian TMCs we propose a basic topology of the generic TMC protein with variable intracellular amino- and carboxyl-termini, a conserved core with eight membrane-spanning domains, and some variability in the length of several intra- and extracellular loops (Figure 2).

  • The initial accumulation of LHCPs in the chloroplast envelope implies that Chl interacts with these proteins, likely by binding to the conserved motif in the first membrane-spanning region (helix-1) [ 25 26 ] when transit through the envelope is initiated.

  • All identified proteins have eight predicted membrane-spanning domains (TM1 - TM8) and share the completely conserved amino acid triplet C (cysteine) - W (tryptophan) - E (glutamic acid), predicted to be located in the extracellular loop upstream of TM6 (Figure 2).

  • The TMC protein family has eight members in vertebrates and forms three subfamilies, A, B, and C. TMCs are proteins with a conserved core of eight membrane-spanning domains.

  • However, the question of what plasma membrane-spanning protein serves as the scaffold for Shc binding and beyond remains to be answered.


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