Example sentences for: localizes

How can you use “localizes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • During Drosophila oogenesis, filamin localizes to the ring canals, which are membrane-associated actin cytoskeletal structures that create intercellular bridges between germline cells.

  • During the course of this study, the gene mutated in LGMD1B was identified as Lamin A/C [ 24 ] . Our investigation, however, revealed that an unrelated gene, YL-1, intergenically spliced into TMOD4 . YL-1 is a putative transformation suppressor gene that localizes to the nucleus and binds to DNA [ 25 26 ] . YL-1 is organized into six exons and produces several alternatively spliced transcripts using both intergenic and cryptic splicing.

  • Expression of epitope-tagged YLR106p is shown to result in a polypeptide of the anticipated size that localizes principally in the nucleus.

  • Like wild-type Pop2p, the reverse Pop2p-N/Pop1p-C chimera localizes to both the nucleus and the cytoplasm, again indicating that Pop1p, but not Pop2p, has a functional NLS in its N-terminus (R.L.

  • Thus, a reduction in human RNase III levels in vivo causes the accumulation of specific rRNA processing intermediates [ 18 ] . Consistent with this functional role, human RNase III localizes to the nucleolus in a cell-cycle-dependent manner [ 18 ] . A truncated form of human RNase III has been purified and shown to cleave dsRNA in vitro [ 18 ] . However, little else is known of the functional roles or the mechanistic features of this enzyme.


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