Example sentences for: localizes

How can you use “localizes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The K695T protein localizes in a pattern similar to the normal protein yet increases the SCE frequency, suggesting that the dominant negative effect of this allele caused the cell lines made in the previous study to die.

  • The normal GFP-BLM fusion protein localizes to NBs and the nucleolus (Figure 4B) as previously reported for BLM in normal human fibroblasts [ 20].

  • . Because GIT-2 localizes with a subset of paxillin, therefore, makes it a potential candidate signaling protein that may collaborate with focal adhesion signaling machinery [ 35 ] . Thus, GIT-2 may play a role in cell adhesion, spreading, and motility.

  • Possibly, the Rad26/Rad3 complex localizes to regions of heterochromatin (centromeres, telomeres and the mating type loci) in undamaged cells.

  • In yeast, profilin null mutations result in cells that are viable at permissive temperature, but grow more slowly, are larger than wild type, and are often multinucleate [ 38 ] . The chickadee ( chic ) gene encodes Drosophila profilin and chic mutations produce sterile female flies [ 39 40 ] . In both species, profilin mutations resulted in defects in actin polymerization [ 38 39 40 ] . In addition to regulating actin assembly, a large body of in vitro and in vivo evidence suggests a role for profilin in signal transduction, mainly involving PIP2, a major second messenger that strongly binds to profilin [ 41 ] and localizes to the membrane microdomains described earlier.


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