Words similar to localize
Example sentences for: localize
How can you use “localize” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several heat shock proteins have been found in cell nuclei in the absence of stress [ 30 ] , and alpha-crystallin has been shown to interact directly with DNA [ 18 ] . AlphaB, expressed in transfected CHO cells, has been shown to ectopically localize to interphase nuclei, suggesting a regulatory role for this protein in the nucleus [ 19 ] . A subset of immortalized lens epithelial cells from alphaBKO mice have been shown to hyperproliferate [ 20 ] suggesting that alphaB may be important in maintaining genomic stability.
Although still able to localize to the nucleus, it prevents subsequent transcription of GC and progesterone responsive genes.
This interaction helps localize Tec family kinases to the membrane where phosphorylation by Src kinases can occur.
DNA repair activities may take place at these foci since BRCA1 has been shown to co-localize with ATR in damage-induced foci [ 58 ] . Using elegant methods to test for direct association of DNA damage checkpoint proteins at double strand breaks in vivo , other groups have shown that MEC1 Rad3-HA and LCD1 Rad26-GFP localize to sites of DNA damage [ 59 60 ] . However, MEC1 was required for this re-localization of LCD1-GFP in vivo [ 60 ] . Thus, while re-localization of Rad26/Rad3-related complexes to sites of DNA repair may be evolutionarily conserved, the regulation of these complexes is not.
Efforts to further localize the gene in this region will require the identification and typing of additional microsatellite markers and single nucleotide polymorphisms (SNPs) in a large cohort of SLE cases and controls.
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