Words similar to localize
Example sentences for: localize
How can you use “localize” in a sentence? Here are some example sentences to help you improve your vocabulary:
By creating a bank of ts mutants in a doubly tagged GFP-nic96 nup170-GFP S. cerevisiae strain and individually screening the mutants at the non-permissive temperature, we identified 121 ts mutant strains which fail to correctly localize the GFP-Nups at NPCs and/or the NE rim.
Mutant forms of myosin II that do not assemble into bipolar thick filaments in vitro fail to rescue myosin null phenotypes, nor do they localize to the furrow during cytokinesis [ 6 7 ] ). Although myosin II is not essential for cell division on a surface, it is critical for normal timely cell separation and for symmetric placement of the division furrow [ 8 ] . GFP-myosin II is transported to the furrow of dividing cells growing on surfaces even though it is not essential for cytokinesis under these conditions.
The assembly of myosin II monomers into filaments is regulated by phosphorylation of its heavy chains at three threonine residues at the C-terminus of the tail [ 9 10 ] . Dephosphorylation of these threonines is a prerequisite of filament assembly, as confirmed by the phenotypes of a 3xAsp mutant, in which the three threonines are replaced by three aspartate residues (mimicking the phosphorylated state) [ 11 ] . In vitro the 3xAsp myosin II is severely impaired for filament assembly, and in vivo 3xAsp myosin II fails to assemble or localize to the cortical cytoskeleton.
Given the current inability to localize transcripts with similar abundances on different arrays, care should be taken to ensure a sufficient overall number of replicates to obtain a small standard error for 0.1 pM level measurements.
The full-length mammalian COP1 protein can localize to the nuclear envelope
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