Words similar to lcls

Example sentences for: lcls

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We, therefore, extended the microarray analyses to lymphoblastoid cell lines (LCLs) and studied four clonal mutant MeCP2 (T158M, 803delG, R168X and 1159del28) expressing and one clonal (1159del28) and four completely skewed (R106W, R255X, 803delG, 803delG) wild-type MeCP2 expressing LCLs.
To assess MeCP2 expression at the protein level, immunoblot analysis with an antibody against the C-terminal region of MeCP2 was carried out on total cell lysates from all eight fibroblast clones, and from some of the LCLs, that were used for array hybridization (Fig.
For the 20 different comparisons, we included three mutant-allele expressing clones (T158M, 803delG, R168X) and four completely skewed wild-type MeCP2 expressing LCLs (R106W, R255X, 803delG, 803delG) from different donors.
Because of skewed X inactivation in the available LCLs, however, we were only able to obtain one matched pair of mutant versus wild-type expressing clones (for 1159del28).
A different design was used for the microarray study of Rett syndrome LCLs.