Example sentences for: iva

How can you use “iva” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, paclitaxel-resistant lung cancer cells and ovarian tumors were shown to have increased levels of tubulin isotypes, particularly β-tubulin classes III and IVa [ 28 ] . Furthermore, when paclitaxel-resistant lung cancer cells were treated with antisense oligonucleotides for β-tubulin class III, the drug resistance was partly reversed, coincident with decreased protein levels of β-tubulin class III [ 65 ] . However, it should be noted that β-tubulin classes I, II, III, and IVa all increased significantly in paclitaxel-resistant lung cancer cells, indicating that the drug effect did not uniquely involve a single tubulin isotype.

  • PCR reactions were performed with isotype-specific primer pairs for β-tubulin isotype classes I, II, III, IVa, and IVb as described [ 46 ] , with minor modifications to correct mismatches and to match the melting temperatures more closely.

  • In other work, β-tubulin classes III and IVa were shown to increase in paclitaxel-resistant prostate cancer cells [ 29 ] . However, these two isotypes continued to be expressed in the lowest amounts.

  • We developed protocols for quantitative two-step reverse transcriptase PCR to establish the relative amounts of mRNA transcripts encoding each of the β-tubulin isotypes (classes I, II, III, IVa, IVb, V, and VI).

  • The lowest levels were found for β-tubulin classes IVa and VI.


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