Words similar to ivb

Example sentences for: ivb

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We developed protocols for quantitative two-step reverse transcriptase PCR to establish the relative amounts of mRNA transcripts encoding each of the β-tubulin isotypes (classes I, II, III, IVa, IVb, V, and VI).
β-Tubulin class II predominates in brain tissues and has been found in smaller amounts in other tissues [ 19 45 ] . Classes III and IVa are primarily found in neurons, whereas classes I and IVb are found in many tissues [ 10 19 ] . β-Tubulin class V is present in small amounts in many cell types [ 11 ] and class VI is found in blood cells and hematopoietic tissues [ 49 50 ] . Much of this quantitative work was done by comparing mRNA levels.
Furthermore, transfection of CHO cells with β-tubulin classes I, II, or IVb did not produce resistance to paclitaxel [ 32 ] . The alternative hypothesis, derived from the work of Cabral and colleagues, is that rather than the tubulin isotype levels, the amount of polymerized tubulin is the critical factor that regulates response to antimitotic drugs.
PCR reactions were performed with isotype-specific primer pairs for β-tubulin isotype classes I, II, III, IVa, and IVb as described [ 46 ] , with minor modifications to correct mismatches and to match the melting temperatures more closely.