Words similar to ionotropic
Example sentences for: ionotropic
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This fact is reflected in the analysis of literature profiles, as groups of genes could be found to be associated with brain tissues (Figure 7f, for example, HPCA (hippocalcin), SYP (synaptophysin), GRIK1 (glutamate receptor, ionotropic, kainate 1), APLP (amyloid beta A4 precursor-like protein)), immune cells (Figure 7b, for example, CD40, IL15RA (IL-15 receptor, alpha chain), LILB4 (leukocyte immunoglobulin-like receptor 4)) or tumor cells (Figure 7a, for example, MYBL1 (v- myb avian myeloblastosis viral oncogene), ABL2 (v- abl Abelson murine leukemia viral oncogene homolog 2)).
The group I mGluRs typically are located postsynaptically (as well as in other compartments of the cell) [ 16 17 18 ] where they regulate activity of ionotropic receptors and are necessary in some forms of synaptic plasticity [ 19 ] . The association of mGluRs with scaffolding proteins such as Homer (group I; [ 20 ] ) and PICK-1 (group III; [ 21 ] ) is important in regulating mGluR localization and function [ 21 22 23 24 ] . In addition to those proteins involved in scaffolding, other proteins have been shown to associate with mGluRs.
Increases in the amount of protein for ionotropic receptor subunits were observed in the membrane fraction isolated from retinae of the rdta mice.
Two types of ionotropic glutamate receptors have been classified: (1) NMDA receptors, which bind glutamate and the glutamate analogue N-methyl-D-aspartate (NMDA); (2) non-NMDA receptors, which are stimulated by kainate, AA-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), and quisqualate, but not NMDA.
The ionotropic AMPA glutamate receptor GluR4 subunit has been shown to be expressed by activated rat adult microglia
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