Example sentences for: immunoglobulin

How can you use “immunoglobulin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An anti-CD81 antibody was first isolated for its ability to induce cell death in B cell lines [ 11 ] . This is likely dependent upon CD81's association with MHC class II molecules, which can transmit death-inducing signals in B cells [ 12 ] . CD81 cross-linking can also induce adhesion in B and T cells, apparently by multiple pathways [ 10 13 14 ] . Triggering of the CD19-CD21-CD81 complex on murine B cells has been shown to lower the threshold for B cell activation via the immunoglobulin receptor [ 15 ] .

  • The importance of the Tec kinases in antigen receptor signaling was first demonstrated by the observation that mutations in BTK result in the human disease X-linked agammaglobulinemia (XLA) and the murine counterpart X-linked immunodeficiency ( xid ). These severe B cell immunodeficiencies are characterized by diminished numbers of mature B cells and reduced immunoglobulin levels associated with impaired PLC-γ activation and Ca ++mobilization in response to surface IgM stimulation (sIgM) [ 8, 9, 10, 11].

  • Polymerase chain reaction conditions for immunoglobulin V Hgene fingerprinting assay

  • IgM - immunoglobulin of the M isotype; ova - chicken ovalbumin; PY - phosphotyrosine; PLCγ2 - phospholipase C γ2; anti - antibody or antiserum generated against indicated antigen; RT-PCR - reverse transcriptase polymerase chain reaction; ICKA - immune-complex kinase assay; ITAM - immunoreceptor tyrosine-based activation motifs; SH2 and SH3 - Src homology domains 2 and 3; PBS - phosphate-buffered saline.

  • During the first few encounters with a foreign protein (or allergen), the immune system catalogs its characteristics and tailors an antibody called immunoglobulin to purge it.


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