Example sentences for: immunohistochemical

How can you use “immunohistochemical” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Double immunohistochemical staining

  • Immunohistochemical detection of apoptosis

  • By applying in situ hybridization, Tuck and colleagues identified breast tumor cells as a source of OPN [ 13 ] . Using a semiquantitative scoring system to evaluate immunohistochemical staining, these investigators found a correlation between OPN positivity (defined as >33% of tumor cells in a section staining for OPN) in lymph node-negative primary breast carcinomas and patient survival, suggesting that tumor cells with elevated OPN levels may behave differently with regard to disease progression [ 13 ] . Another recent study showed immunohistochemically that while OPN protein is expressed weakly in normal breast tissue, OPN is expressed strongly (>50% tumor cell staining) in pregnant/lactating tissue and in the majority (66%) of breast carcinomas.

  • Our findings are consistent with those of a recent study showing that a vast majority of the ME cells in both normal and ductal carcinoma in situ displayed distinct immunostaining to p63, SM-MHC, and calponin, whereas a single or a cluster of a few ME cells in some ducts failed to show immunoreactivity to all these three markers [ 28 ] . However, our study differs from this study [ 28 ] and previous studies [ 3 4 ] in four aspects: first, the SMA-negative cells were segmented, accounting for at least one-third or all of the ME cells in involved ducts; second, we tested for more ME cell markers; third, the SMA-negative cells assessed were morphologically similar to their adjacent SMA-positive neighbors on H&E-stained sections; fourth, our focus is directed toward the elucidation of the detailed immunohistochemical profile of these SMA-negative cells identified in 3 of 175 examined cases.

  • Immunohistochemical staining


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