Words similar to igf-i
Example sentences for: igf-i
How can you use “igf-i” in a sentence? Here are some example sentences to help you improve your vocabulary:
IGF-I produces a chemotactic response in human melanoma cells and antisense to the IGF-IR mRNA prevents metastasis in the murine carcinoma cell H-59.
Treatment with antagonistic peptide analogs of IGF-I, antisense oligos, or an adenovirus expressing IGF-IR antisense cRNA, prevents proliferation of cells in monolayers, transformation, and growth in athymic nude mice.
We have previously demonstrated the overexpression and hormone-independent activation of the IGF-IR in primary breast cancers [ 42 ] . Similar overexpression of the IGF-IR and the ligands IGF-I and IGF-II have been seen in human gliomas and astrocytomas [ 43 44 45 46 ] . Because of the important role for the IGF-IR in cell survival, we investigated whether a dominant negative IGF-IR could inhibit growth of the U87 glioma.
Inhibition of the IGF-I receptor by expression of a kinase inactive mutant inhibits proliferation of Chinese hamster ovary (CHO) cells
Insulin and IGF-I bind and stimulate tyrosine kinase receptors which interact with a large number of effectors [ 6 7 ] . Complex interactions occur between these two types of signaling pathways that are the subject of intense investigation.