Example sentences for: igf-i

How can you use “igf-i” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Inhibition of the IGF-I receptor by expression of a kinase inactive mutant inhibits proliferation of Chinese hamster ovary (CHO) cells

  • This antibody prevents binding of IGF-I or IGF-II to the extracellular domain of the IGF-IR, and has been shown to prevent the formation of MDA231 tumors in nude mice [ 55 ] . U87 cells were plated in soft agar in the presence of αIR3 or a control antibody.

  • Insulin and IGF-I bind and stimulate tyrosine kinase receptors which interact with a large number of effectors [ 6 7 ] . Complex interactions occur between these two types of signaling pathways that are the subject of intense investigation.

  • Retroviral expression of the kinase inactive IGF-I Receptor inhibits growth of U87 glioblastoma cells in-vivo

  • To confirm that the kinase-defective receptors were functioning in a dominant-negative fashion, we studied the ability of CHO and CHO-MK cells to incorporate 3H-thymidine into DNA in response to IGF-I stimulation.


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