Words similar to igf-i
Example sentences for: igf-i
How can you use “igf-i” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results confirm that inhibition of IGF-I signaling by an inhibitory antibody can suppress growth of a PTEN-deficient glioma cell line.
Retroviral expression of the kinase inactive IGF-I Receptor inhibits growth of U87 glioblastoma cells in-vivo
Infection with the MK virus eliminated the IGF-I stimulated phosphorylation of IRS-1 confirming that the expressed receptor was acting as a dominant negative to inhibit the endogenous receptors.
This antibody prevents binding of IGF-I or IGF-II to the extracellular domain of the IGF-IR, and has been shown to prevent the formation of MDA231 tumors in nude mice [ 55 ] . U87 cells were plated in soft agar in the presence of αIR3 or a control antibody.
Because the M6P/IGF2R is believed to sequester and degrade IGF-II [ 10 ] , a decrease in M6P/IGF2R could result in decreased degradation and hence increased bioavailability of IGF-II to the IGF-I receptor, which mediates the growth-promoting effect of IGF-II.