Words similar to iga
Example sentences for: iga
How can you use “iga” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although frequencies of positivity for A*01-B*08 were slightly greater in index patients who had deficiencies of IgG, IgA, or IgM, these differences were not significant (Table 7).
Diagnoses were based on demonstration of persistent, otherwise unexplained serum concentrations of immunoglobulins > 2 S.D. below the corresponding mean levels [ 1 ] . Criteria for the diagnosis of CVID were: 1) decreased total serum IgG concentration; and 2) either decreased IgG subclass(es), decreased serum IgA concentration, or decreased serum IgM concentration [ 1 ] . Criteria for the diagnosis of IgGSD were: 1) normal total serum IgG concentration; and 2) abnormally low serum concentrations of one or more IgG subclasses; some patients with IgGSD also had decreased levels of IgA or IgM levels [ 1 ] .
Some reports suggest that IgA deficiency segregates with a HLA haplotype(s) containing A*01, B*08 in some families [ 4 5 6 19 20 ] . Thus, we analyzed the frequencies of the haplotype A*01-B*08 in the present index patients grouped according to presence of normal or subnormal pre-treatment serum concentrations of IgG, IgA, and IgM, respectively.
We also excluded persons who had isolated deficiencies of IgA or IgM, those with hypogammaglobulinemia attributable to B-cell neoplasms ( e.g ., B-chronic lymphocytic leukemia, plasma cell myeloma, macroglobulinemia, or non-Hodgkin's lymphoma) or those with markedly increased immunoglobulin loss ( e.g ., nephrotic syndrome or protein-losing enteropathy).
Regardless, the variability we observed in IgG, IgA, and IgM phenotypes in index patients and family members is best explained by the co-inheritance of multiple allele(s) that influence the immunoglobulin phenotype.
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