Words similar to iga
Example sentences for: iga
How can you use “iga” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although frequencies of positivity for A*01-B*08 were slightly greater in index patients who had deficiencies of IgG, IgA, or IgM, these differences were not significant (Table 7).
Diagnoses were based on demonstration of persistent, otherwise unexplained serum concentrations of immunoglobulins > 2 S.D. below the corresponding mean levels [ 1 ] . Criteria for the diagnosis of CVID were: 1) decreased total serum IgG concentration; and 2) either decreased IgG subclass(es), decreased serum IgA concentration, or decreased serum IgM concentration [ 1 ] . Criteria for the diagnosis of IgGSD were: 1) normal total serum IgG concentration; and 2) abnormally low serum concentrations of one or more IgG subclasses; some patients with IgGSD also had decreased levels of IgA or IgM levels [ 1 ] .
Biological studies have demonstrated increased levels of CD3+/CD25+ lymphocytes [ 5 ] , HTLV-I proviral load and HTLV-I tax/rex mRNA expression [ 6 7 ] , HTLV-I specific IgA [ 8 ] , soluble interleukin-2 receptors [ 9 ] , beta-chemokines [ 7 ] and soluble intracellular adhesion molecule-1 (ICAM-1) [ 10 ] , in bronchoalveolar lavage fluid from HTLV-I infected humans.
Common variable immunodeficiency (CVID) and selective immunoglobulin G subclass deficiency (IgGSD) are characterized by subnormal serum concentrations of total IgG, or by normal serum total IgG concentrations with deficiency of one or more IgG subclasses, respectively; in some cases, IgA or IgM levels are also subnormal [ 1 2 3 ] . Most persons are diagnosed to have CVID or IgGSD because they have increased frequency and severity of infections due to bacteria and other microbial pathogens [ 1 4 ] . Although a susceptibility locus for these disorders has not been identified, they often appear to be familial and to segregate with markers on Ch6p [ 1 5 6 ] .
Taken together, these observations could explain the occurrence of CVID or IgGSD and hemochromatosis due to HFE C282Y homozygosity in some of the present index patients [ 26 ] and account for the occurrence of IgA deficiency and hemochromatosis in different members of the same family [ 27 ] .
Loading...