Words similar to igf

Example sentences for: igf

How can you use “igf” in a sentence? Here are some example sentences to help you improve your vocabulary:

M6P/IGF2R allelic loss would therefore result in enhanced cellular bioavailability of this potent growth factor, thereby potentially increasing both cell proliferation and resistance to apoptosis [ 29 ] . The M6P/IGF2R also facilitates the activation of TGFβ, a potent cell growth inhibitor that is secreted in an inactive form (reviewed in [ 15 16 ] ). M6P/IGF2R mutation is therefore one mechanism by which cancer cells can become refractory to TGFβ's mitoinhibitory effect.
4A, cells infected with Ad-GFP/Rz-IGF2R had a corresponding reduction of ~40% in 125I-IGF-II internalization when compared with control cells (infected with Ad-GFP).
In fact, activation of TGF-β requires the binding of latent TGF-β to the M6P/IGF2 receptor [ 11 ] . Therefore, down-regulation of M6P/IGF2R expression could also lead to a decreased bioavailability of activated TGF-β, thereby decreasing the sensitivity of MCF-7 cells to the TGF-β apoptotic pathway.
Moreover, if some chemotherapeutic agents are not only directly cytotoxic to cancer cells, but also reduce tumor production of growth factors, such as IGF2 and TGFβ, adjuvant chemotherapy would be more useful in treating tumors with a mutated M6P/IGF2R , as observed in this study.
One peptide was chosen from each of the APP, HCV and IGF pans (based on the highest specific binding vs.