Words similar to igf-ii

Example sentences for: igf-ii

How can you use “igf-ii” in a sentence? Here are some example sentences to help you improve your vocabulary:

After infection with Ad-GFP/IGF2R-Rz or Ad-GFP, cells were incubated with or without 50 ng/ml IGF-II for 4 days.
M6P/IGF2R-null mice display global hyperplasia that coincides with elevated levels of IGF-II.
Measurement of 125I -IGF-II internalization
This is consistent with previous observations that M6P/IGF2R knockout mice displayed generalized increased growth and cardiomygaly (resulting from cardiac myocyte hyperplasia) [ 34 ] , and that antisense-mediated reduction of M6P/IGF2R expression enhances tumorigenicity in JEG-3 cells [ 43 ] . Thus, loss or mutation of M6P/IGF2R may contribute to development and progression of tumors via different pathways: by increasing the mitogenic activity of IGF-II and decreasing the apoptotic signaling of TGF-β and lysosomal proteases.
Although we do not rule out the potential contribution of the IGF-II pathway to this effect, we would like to consider other potential M6P/IGF2R-dependent mechanisms, such as lysosomal proteases and TGF-β signaling, that may directly affect cell sensitivity to apoptosis.