Words similar to igf-ii

Example sentences for: igf-ii

How can you use “igf-ii” in a sentence? Here are some example sentences to help you improve your vocabulary:

This result suggests that the proliferative effect of M6P/IGF2R down-regulation is likely the result of unchecked IGF-II stimulation.
This is consistent with previous observations that M6P/IGF2R knockout mice displayed generalized increased growth and cardiomygaly (resulting from cardiac myocyte hyperplasia) [ 34 ] , and that antisense-mediated reduction of M6P/IGF2R expression enhances tumorigenicity in JEG-3 cells [ 43 ] . Thus, loss or mutation of M6P/IGF2R may contribute to development and progression of tumors via different pathways: by increasing the mitogenic activity of IGF-II and decreasing the apoptotic signaling of TGF-β and lysosomal proteases.
After infection with Ad-GFP/IGF2R-Rz or Ad-GFP, cells were incubated with or without 50 ng/ml IGF-II for 4 days.
Specific internalized 125I-IGF-II was calculated by subtracting the counts of samples with excessive unlabeled IGF-II from that without unlabeled IGF-II, and normalized to protein content.
Ad-GFP, adenovirus carrying GFP gene; Ad-GFP/Rz-IGF2R, adenovirus carrying both ribozyme against M6P/IGF2R and GFP gene; GFP, green fluorescent protein; IGF-II, insulin-like growth factor II; M6P/IGF2R, mannose 6-phosphate/insulin-like growth factor II receptor; Rz, ribozyme, TGF-β transforming growth factor beta.