Words similar to igf-ir
Example sentences for: igf-ir
How can you use “igf-ir” in a sentence? Here are some example sentences to help you improve your vocabulary:
After surgery, autologous glioma cells were collected and treated ex-vivo with IGF-IR antisense oligos and re-implanted in diffusion chambers for 24 h.
To test the function of the virally encoded receptors, we measured IGF-I stimulated autophosphorylation of the IGF-IR and phosphorylation of IRS-1.
The tumors from U87 cells infected with the kinase inactive IGF-IR are less cellular with larger areas of stroma (left panel).
[for reviews see refs [ 31 ] , [ 39 40 41 ] ]. The IGF-IR appears to function in transformation both by preventing apoptosis through activation of Akt and by stimulating proliferation through the ras-MAPK cascade.
The irregular nuclei and intact capsule are consistent with data from other cells showing that inhibition of IGF-IR expression causes apoptosis and prevents metastasis.