Example sentences for: igf-ir

How can you use “igf-ir” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After surgery, autologous glioma cells were collected and treated ex-vivo with IGF-IR antisense oligos and re-implanted in diffusion chambers for 24 h.

  • To test the function of the virally encoded receptors, we measured IGF-I stimulated autophosphorylation of the IGF-IR and phosphorylation of IRS-1.

  • The tumors from U87 cells infected with the kinase inactive IGF-IR are less cellular with larger areas of stroma (left panel).

  • [for reviews see refs [ 31 ] , [ 39 40 41 ] ]. The IGF-IR appears to function in transformation both by preventing apoptosis through activation of Akt and by stimulating proliferation through the ras-MAPK cascade.

  • The irregular nuclei and intact capsule are consistent with data from other cells showing that inhibition of IGF-IR expression causes apoptosis and prevents metastasis.


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