Example sentences for: igf-ir

How can you use “igf-ir” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [for reviews see refs [ 31 ] , [ 39 40 41 ] ]. The IGF-IR appears to function in transformation both by preventing apoptosis through activation of Akt and by stimulating proliferation through the ras-MAPK cascade.

  • After surgery, autologous glioma cells were collected and treated ex-vivo with IGF-IR antisense oligos and re-implanted in diffusion chambers for 24 h.

  • Treatment with antagonistic peptide analogs of IGF-I, antisense oligos, or an adenovirus expressing IGF-IR antisense cRNA, prevents proliferation of cells in monolayers, transformation, and growth in athymic nude mice.

  • The tumors from U87 cells infected with the IGF-IR virus are also very cellular, but the cells have larger nuclei (left panel) and have completely invaded the capsule (right panel).

  • What is the evidence for the involvement of IGF-IR signaling in proliferation and cancer?


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