Words similar to igf-ir

Example sentences for: igf-ir

How can you use “igf-ir” in a sentence? Here are some example sentences to help you improve your vocabulary:

To test initially whether the PTEN-deficient U87 glioma cells might be susceptible to inhibition of the IGF-IR, we measured colony formation and tumor growth in the presence of an inhibitory antibody to the human IGF-IR (αIR3).
The idea that the IGF-IR might be a valuable target for the treatment of brain tumors is supported by a recent pilot study in twelve patients with malignant astrocytomas [ 56 ] . All patients had grade 3 or 4 astrocytomas and had failed on standard therapy.
The tumors from U87 cells infected with the IGF-IR virus are also very cellular, but the cells have larger nuclei (left panel) and have completely invaded the capsule (right panel).
The results obtained with the dominant negative IGF-IR are identical to published results reintroducing PTEN, hence, inhibition of upstream PI-3Kinase signaling might be a useful approach for PTEN-deficient tumors.
The tumors from U87 cells infected with the kinase inactive IGF-IR are less cellular with larger areas of stroma (left panel).