Words similar to hypertrophic
Example sentences for: hypertrophic
How can you use “hypertrophic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our results suggest that iron deficient, hypertrophic hearts display a hyper-sensitive inotropic, but not chronotropic, response to norepinephrine.
Furthermore, persisting tension in the wound bed may explain why hypertrophic scars maintain the myofibroblast phenotype long after wound closure.
Whether the elevated Ihh mRNA levels originate from increased expression in cells that make Ihh normally (prehypertrophic and hypertrophic chondrocytes) or from ectopic activation by the Hox transcription factors in proliferating cells, remains to be investigated.
Many studies have shown that chronic intravenous infusion of norepinephrine is sufficient to cause hypertrophy, and that various forms of hypertrophy are linked to a decrease in either beta-adrenergic receptor density or a decreased responsiveness to beta-adrenergic stimulation [ 46 48 49 56 57 58 59 60 61 62 63 ] . Barth, for example, showed that norepinephrine infusion induced left ventricular hypertrophy that could be prevented by an adrenergic-receptor blocker [ 58 ] . It has been suggested that ornithine decarboxylase is a link between beta-adrenoreceptors and stimulation of tissue growth factor, which results in hypertrophy [ 64 ] . However, recent studies have focused on alpha-adrenergic reception as a mediator of cardiac hypertrophy [ 35 ] , although some question the role of the alpha-adrenergic receptor as a hypertrophic mediator in vivo [ 34 ] . To date, no published studies of which we are aware have examined alpha-adrenergic reception and the development of cardiac hypertrophy with iron deficiency.
This would be expected chronically to result in a eccentric hypertrophic pattern, a condition that we and others [ 15 17 ] have found in iron deficient rat hearts.
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