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Example sentences for: hyperthermophilic
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The single archaeal fusion, the Arachaeoglobus fulgidus protein AF0227, belongs to one of these clusters and shows a strongly supported affinity with the ortholog from the hyperthermophilic bacterium Thermotoga maritima . (Figure 4a,4b).
Nevertheless, an evolutionary affinity between Cyanobacteria ( Synechocystis ) and Actinomycetes ( Mycobacterium ) appears plausible, particularly given the presence, in these bacterial groups, of well-developed and partly similar signal transduction systems [ 27 ] . The connection between two hyperthermophilic bacteria, Aquifex and Thermotoga, also has obvious biological meaning, although, in this case, particular caution is due, given the possibility of preferential horizontal gene exchange between these organisms that inhabit similar environments.
The closest to the root were the two hyperthermophilic species, A. aeolicus and T. maritima, which is compatible with the standard view of their phylogenetic position [ 1 26 ] .
The hyperthermophilic topoisomerase I from Thermotoga maritima has been shown to coordinate one Zn(II) with a unique tetracysteine motif Cys-X-Cys-X 16 -Cys-X-Cys but Zn(II) binding is not required for relaxation activity [ 33 ] . The sequence of this unique tetracysteine motifs is somewhat different from those present in other type IA topoisomerases in that the other tetracysteine motifs always had at least two amino acids separating the pairs of cysteines (Cys-X 2-11 -Cys), instead of just one amino acid (Cys-X-Cys) in T. maritima topoisomerase I [ 33 ] . Therefore the structure and function of the single Zn(II) binding motif in T. maritima may differ from the multiple Zn(II) binding motifs in E. coli topoisomerase I. Direct interaction between DNA and the T. maritima Zn(II) binding motif has not been demonstrated.
There is one exception: gene order conservation between the hyperthermophilic bacterium Thermotoga maritima and archaea is higher than the rest, and much higher than between Aquifex and archaea, even though the SSU rRNA distances between bacteria and archaea are approximately equal.
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