Words similar to hypertriglyceridemia
Example sentences for: hypertriglyceridemia
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The higher incidence of hypertriglyceridemia in the APV600/RTV arm was probably due to RTV, because this PI has been reported to cause elevations in serum triglycerides [ 22 ] . Other studies of RTV-boosted APV regimens have also reported that triglyceride elevation is usually grade 1 or 2 in magnitude, and, as in the present study, seldom necessitates treatment discontinuation or the addition of antihyperlipidemic drugs to the patient's treatment plan [ 10 19 ] .
However, review of laboratory changes revealed that the incidence of grade 3-4 hypertriglyceridemia was the same (4%) in each treatment arm.
The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .
More cases of hypertriglyceridemia were reported as adverse events in the APV600/RTV arm (11 [7%] vs 0).
1a), have been tested clinically, and display unacceptable side effects, such as skin dryness, cheilitis, hypertriglyceridemia and conjunctivitis [ 9, 10].
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