Example sentences for: hypertrophy

How can you use “hypertrophy” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We found the expression of p107 mRNA and Bmp-4 mRNA to be decreased, which, if reflected in reduced protein levels, would be consistent with the phenotype of delayed cartilage maturation in Hox transgenic animals: As Bmp-4 was shown to have a positive effect on hypertrophy and inhibitory effect on proliferation [ 37 38 ] , decreased Bmp-4 expression would be expected to promote chondrocyte proliferation.

  • Yet, both males and females demonstrated increased sensitivity to acute isoproterenol injection after repeated administration that resulted in significant cardiac hypertrophy [ 23, 24].

  • The antigen-induced arthritis model of rheumatoid arthritis in rabbits demonstrates persistent active inflammation for several months after the intra-articular injection of antigen, including hypertrophy and hyperplasia of the synovial lining cells, pannus formation with articular cartilage erosion, and chronic infiltration of synovium by lymphocytes and plasma cells [ 13 ] . In addition, Dijkstra and colleagues [ 15 ] found macrophages in the superficial layer of the synovium, where they might secrete enzymes and oxygen radicals into the joint space, which can lead to cartilage erosion [ 9 ] . The protein levels in lavage fluid from arthritic joints in this model are low enough to allow direct testing by Western blot analysis without immunoaffinity purification, as was needed with the human aspirates.

  • In addition to age, left ventricular hypertrophy is also a well-established risk factor for atrial fibrillation in the general population.

  • Similarly, Tse [ 48 ] found that in compensated hypertrophy the population of beta-adrenergic receptors is relatively normal, but in heart failure, the beta receptors have both down-regulated and de-sensitized.


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