Example sentences for: hypervariable

How can you use “hypervariable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This region, commonly referred to as the hypervariable domain, plays a major role in the subcellular targeting and functional specificity of each Rab protein [ 49 ] . In accord with this view, replacement of the hypervariable domain of Rab24(wt) with the corresponding domain from Rab1B, caused the resulting chimera to exhibit a discrete juxtanuclear Golgi-like fluorescence pattern typical of Rab1B in 293 cells [ 50 51 ] . (Fig.

  • Minisatellites of the hypervariable family (20-50 bp repeat size) are dispersed throughout the genome but, as expected [ 51], show sharp spikes in subtelomeric regions of most chromosomes.

  • Identical structures were seen when immunofluorescence microscopy was performed with antibodies against the N-terminal myc epitope or the C-terminal hypervariable domain of Rab24, indicating that the immunofluorescence pattern reflected the localization of full-length mycRab24(D123I).

  • To confirm the importance of the Rab24 hypervariable domain for targeting to inclusion bodies, we performed the reciprocal experiment, replacing the C-terminal domain of Rab1B(wt) or Rab1B(N121I) with the hypervariable domain from Rab24.

  • To determine whether the hypervariable domain of Rab24 was sufficient to promote the formation of inclusion bodies when fused to a heterologous protein, we prepared fusion constructs with enhanced green fluorescent protein (EGFP) containing either full-length Rab24(D123I) or just the Rab24 C-terminal domain.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast