Example sentences for: hydroxykynurenine

How can you use “hydroxykynurenine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The kynureninase of rat and human liver has an order-of-magnitude preference for 3-hydroxykynurenine [ 37], in contrast to a microbial kynureninase that exhibits a very high preference for kynurenine [ 38].

  • Kynureninases have been reported to possess a range of substrate specificities that vary between very high specificity for kynurenine and very high specificity for 3-hydroxykynurenine.

  • 3-Hydroxykynurenine and 3-hydroxyanthranilate have been shown to cause apoptotic or necrotic neuronal death in cell cultures [ 32].

  • It is of interest that the conversion of kynurenine to anthranilate and the conversion of 3-hydroxykynurenine to 3-hydroxyathranilate are similar hydrolytic reactions.

  • 3-Hydroxykynurenine is a prominent metabolite in the eye lens (it absorbs UV radiation) and probably supports eye pigmentation in the iris/ciliary body [ 35].


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