Words similar to hydroxy-
Example sentences for: hydroxy-
How can you use “hydroxy-” in a sentence? Here are some example sentences to help you improve your vocabulary:
HMG CoA = 3-Hydroxy-3-methylgluatryl coenzyme A; MIRACL = Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering; LDL = low density lipoprotein; RR = relative risk; CI = confidence interval; HDL = high density lipoprotein; PTCA = percutaneous transluminal coronary angioplasty; CABG = coronary artery bypass graft; ECG = electrocardiogram; A-2-Z = Aggrastat to Zocor; ACS = acute coronary syndrome; PROVE IT = Pravastatin or Atorvastatin Evaluation and Infection Therapy.
It has been shown that HIV-infected brain has a decrease of mRNA and protein of the GluR-A flop subtype of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) glutamate receptor in cerebellar Purkinje cells.
Patients on dialysis have more coronary artery disease (CAD) and CAD-related mortality than the general population [ 1 ] . Elevated low-density lipoprotein (LDL) cholesterol level is an independent risk factor for patients with end stage renal disease (ESRD) [ 2 ] . The 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been associated with decreased all-cause mortality in dialysis patients in a registry-based study [ 3 ] and clinical trials are underway to confirm this benefit [ 4 5 ] .
The EGFR antagonist, AG1478 (4-(3-chloroanilino)-6,7-dimethoxyquinazoline), the insulin receptor antagonist, hydroxy-2-napthalenylmethylphosphonic acid-tris acetoxymethylester (HNMPA-(AM) 3 ), and the PDGFR antagonist, tyrosphostin, 9 were purchased from Biomol (Plymouth Meeting, PA).
It is generally accepted that the hydroxy acid form of statins are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that plays a critical role in cholesterol metabolism, where they block substrate accessibility to HMG-CoA reductase, effectively subverting cholesterol levels of HDL [ 19 20 21 ] . In addition to lowering cholesterol, statins seem to have a number of additional effects, such as the nitric oxide-mediated promotion of new blood vessel growth [ 22 ] , protection against oxidative modification of low-density lipoprotein, as well as anti-inflammatory effects and a reduction in C-reactive protein levels [ 23 ] . All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .
Loading...