Example sentences for: hydroxy

How can you use “hydroxy” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Detection of the active Simvastatin hydroxy acid metabolite in mouse serum after gavage administration

  • The only two clear exceptions to this pattern of poorly conserved proteins primarily involved in defense and extracellular signaling were the mammalian enzymes hydroxysteroid sulfotransferase and hydroxy acid oxidase.

  • Species of chlamydiae possess one ( C. psittaci ) or two ( C. muridarum, C. trachomatis and C. pneumoniae ) homologs of genes encoding the well characterized hydroxy/aromatic amino acid (HAAAP) permease family [ 48].

  • It is generally accepted that the hydroxy acid form of statins are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that plays a critical role in cholesterol metabolism, where they block substrate accessibility to HMG-CoA reductase, effectively subverting cholesterol levels of HDL [ 19 20 21 ] . In addition to lowering cholesterol, statins seem to have a number of additional effects, such as the nitric oxide-mediated promotion of new blood vessel growth [ 22 ] , protection against oxidative modification of low-density lipoprotein, as well as anti-inflammatory effects and a reduction in C-reactive protein levels [ 23 ] . All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .

  • 2 pmol/L (normal < 2.8); 25-hydroxy Vitamin D 16 ng/mL (reference lab normal range for age 3-17 years = 13-67); and 1,25-dihydroxy Vitamin D level 32 pg/mL (reference lab normal range for age 3-17 years = 27-71).


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