Words similar to hyaluronic
Example sentences for: hyaluronic
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Images showing the results of the digestion of the hyaluronic acid by hyaluronidase activity present were captured by scanning the gels.
In contrast, hyaluronic acid, chondroitin-4-sulfate and chondroitin-6-sulfate had no effect on the ability of III1-C to stimulate ERK1/2 activity (Fig.
The functional property of Hyal-2 in degrading hyaluronic acid is controversial.
Aggrecan and versican are aggregating proteoglycans that are key constituents found in the extracellular matrix [ 41 ] . Both proteoglycans contain amino-terminal hyaluronic acid-binding regions, central core glycosaminoglycan attachment domains, and carboxyl-terminal domains containing EGF-like modules (one in aggrecan and two in versican), C-type lectin like modules and complement regulatory protein-like modules [ 49 50 ] . Fibulin-1 exhibits calcium-dependent binding to the carboxyl-terminal domain of aggrecan and versican [ 41 ] . The binding site of aggrecan to fibulin-1 maps to the type II EGF-like modules 8-9 and the carboxyl-terminal domain of fibulin-1 [ 41 ] . The binding site of versican to fibulin-1 maps to the type II EGF-like modules 2-8 of fibulin-1 [ 41 ] .
Unlike somatic ubiquitous hyaluronidases that are active only at acidic pH [ 8 ] , SPAM1 has hyaluronidase activity at both neutral and acidic pHs, which arise from two different regions within the hyaluronidase domain [ 4 ] . The neutral enzyme activity, which is predominant in insoluble membrane-bound SPAM1, is necessary for sperm to penetrate the hyaluronic acid (HA)-rich extracellular matrix of the cumulus cells surrounding the oocyte.
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