Words similar to hyaloid
Example sentences for: hyaloid
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If macrophages are eliminated with toxic liposomes [ 34 ] or in transgenic mice expressing diphtheria toxin from a macrophage specific transgene [ 46 ] , there is persistence of the pupillary and hyaloid vessels.
Bmp4 +/-heterozygotes have abnormally arranged retinal blood vessels and abnormal persistence of the hyaloid vasculature.
In Bmp4 +/+mice the hyaloid vessels disappeared around P30, as reported elsewhere [ 33 34 ] . In contrast, the hyaloid vessels in Bmp4 +/-heterozygotes persisted throughout the 17 month period studied and increased in number and size beyond that normally present at birth (Figure 4D,E,F,G).
Regression of the hyaloid vasculature is mediated via macrophage-dependent cell death [ 35 ] . In the first ten days after birth, macrophages were abundant in the vitreous of Bmp4 +/+mice, usually localized close to the hyaloid vascular system (Figure 4F).
Elimination of the hyaloid vessels proceeds by programmed cell death in both human [ 45 ] and mouse eyes [ 33 35 ] . Furthermore, this death of endothelial cells and pericytes does not occur in the absence of macrophages.
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