Words similar to hy
Example sentences for: hy
How can you use “hy” in a sentence? Here are some example sentences to help you improve your vocabulary:
In A. thaliana , CSN was shown to be required for the efficient nuclear accumulation of the putative RING-type ubiquitin ligase COP1 [ 24], which mediates ubiquitin-dependent degradation of the photomorphogenic transcription factor HY5 [ 25].
(A quarter century after high school trigonometry, about all I can remember of it is the benevolent Indian “Soh-Cah-Toa”: Sine = o pposite/ hy potenuse, C osine = a djacent/ hy potenuse, T angent= o pposite/ a djacent, relating the lengths of the right triangle's sides to the functions of its angles).
HY conceived this study, HY, BP, and KL performed the molecular genetic studies, EK performed the real time PCR and the western blotting assays, M-HL performed the immunostaining, KH performed the FISH assay, RK and AB performed the sterol analyses, MS and NE performed the DNA isolations from the rats.
Instead, CIP8, an AtCOP1 interacting RING-H2 finger protein, is found to ubiquitinate HY5 in vitro [ 50 51 ] . Therefore, it is possible that COP1 may recruit other RING finger proteins, such as CIP8, to mediate the ubiquitination of specific substrates.
COP10, which has been shown to interact with AtCOP1 in yeast two-hybrid experiment, encodes a ubiquitin conjugating enzyme (E2) variant [ 44 ] . The COP9 signalosome, an eight-subunit complex homologous to the lid subcomplex of the 26 S proteasome [ 45 ] , directly associates with SCF E3 complex and promotes deneddylation of the cullin subunit of SCF in both plant and animal cells [ 46 47 48 49 ] . The exact relationship between COP1 and the COP9 signalosome remains obscure; it is known, however, that in Arabidopsis the COP9 signalosome is required for COP1 to accumulate in the nucleus in the dark [ 29 ] . Although COP1 most likely plays a role in regulating protein degradation, attempts in reconstituting ubiquitination of HY5 by AtCOP1 have been unsuccessful.
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