Example sentences for: hyaluronidase

How can you use “hyaluronidase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cumulus cells were removed by treating eggs for 3 min with 1 mg/ml hyaluronidase (Sigma, St. Louis, MO) in M199; eggs were washed through four 50-ml drops of M199 medium covered with mineral oil using a pulled , heat-polished, Pasteur pipette (employed in all experiments).

  • In Trinidad the following clinical features have been seen: tachypnea, restlessness, vomiting, increased salivation, cerebral oedema, pulmonary oedema, hypovolemic shock and convulsions, with myocarditis and pancreatitis being major complications [ 48 ] . Scorpion venoms may cause these symptoms through release of catecholamines from the sympathetic nervous system [ 11 ] . The venom exerts its effects primarily to the cardiovascular and respiratory systems, but there is also stimulation of both the sympathetic and parasympathetic peripheral activities [ 11 ] . The venom is a complex mixture of phospholipase A 2 , low molecular weight proteins, acetylcholinesterase, hyaluronidase, toxic polypeptides, amino acids, serotonin and neurotoxins [ 11 48 ] . Two fatal cases suggested toxic myocarditis [ 48 ] .

  • 02% (w/v) EDTA solution (Sigma Chemical Co., St. Louis, MO) containing 1 mg/ml collagenase (Sigma) and 0.3 mg/ml hyaluronidase (Sigma) for 2 h at 37°C.

  • The Sperm Adhesion Molecule 1 (SPAM1 or PH-20) is a glycosyl-phosphatidylinositol (GPI)-linked protein found on all mammalian spermatozoa that have been examined, and has been reported to play multiple roles in fertilization [ 1 ] . Although a recent gene targeting study indicates that in mice, which have four active non-somatic hyaluronidases, Spam1 is not essential for fertilization [ 2 ] ; this is unlikely to be the case in humans where SPAM1 is the only such hyaluronidase present.

  • Interestingly, malignant and metastatic breast and prostate cancer cells frequently overexpress both hyaluronidase and TGF-β proteins [ 3 4 5 6 7 ] . Previously we have shown that bovine testicular hyaluronidase, also known as PH-20, increases the susceptibility of various cancer cells to tumor necrosis factor (TNF or TNF-α) cytotoxicity [ [ 8 ] , review].


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