Words similar to hsc
Example sentences for: hsc
How can you use “hsc” in a sentence? Here are some example sentences to help you improve your vocabulary:
The chaperon proteins such as Hsc73 could be involved in unfolding the substrates for them to fit into the degradation chamber and the final maturation of 20S proteasome from the 16S assembly intermediates could trap the substrates, such as Ump1 and Smads, inside the degradation chamber.
A small protein Ump1 associates with the premature proteasome complexes and is shown to be involved in assisting the maturation of 20S proteasome, possibly by interacting with the β rings of half proteasomes [ 46 ] . Upon the maturation of the 20S proteasome, Ump1 is trapped inside the proteasome and is degraded by proteasome [ 46 ] . The HSP70 like chaperon protein Hsc73 also associates with the 16S proteasome precursor complexes [ 35 36 ] . The exact role of Hsc73 in 16S precursor proteasome complex is not known, but has been suggested to assist proteasome maturation [ 35 36 ] . Our studies add Smad1, Smad1 interacting proteins such as SNIP1, Smad4, and Az as additional proteins that associate with the assembly intermediates.
Members of the HSP70 family have also been proposed to be involved with HSP90 chaperones regulating signal transduction pathways [ 32 ] . Unlike HSP70, HSC70 does not exhibit increased gene expression when exposed to heat stress or other agents such as sodium arsenate in the gastrula and neurula Xenopus embryo [ 33 ] . Tsang [ 34 ] suggested because of their ability to bind and transport folded and un-folded cellular proteins, HSP70 family members may function as a cross-linker to couple cellular proteins to the cytoskeletal matrix.
Messenger RNA expression profiles of SAHH, HSC70 and OSU-T1-50 were generated using the ABI PRISM 7700 Sequence Detection System (PE Applied Biosystems).
Negative mutations of HSC70 in the nervous system of Drosophila larvae resulted in both developmental defects and lethality [ 31 ] . The increased HSC70 gene expression during trophoblastic elongation is temporally associated with neural tube development in pig conceptuses.
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