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Example sentences for: hsc

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HSC70 gene expression was also significantly enhanced (P < 0.001) in filamentous conceptuses (Table 4), which displayed an approximate 10-fold increase in gene expression compared to spherical, ovoid and tubular morphologies (Figure 2).
Negative mutations of HSC70 in the nervous system of Drosophila larvae resulted in both developmental defects and lethality [ 31 ] . The increased HSC70 gene expression during trophoblastic elongation is temporally associated with neural tube development in pig conceptuses.
Quantitative analysis of clones of interest, specifically, s-adenosylhomocysteine hydrolase (SAHH), heat shock cognate 70 KD protein (HSC70), and one unknown transcript, OSU-T1-50, were assayed using quantitative real-time RT-PCR [ 14 ] . Individual and small pools of conceptuses were evaluated at the four morphologically distinct stages; spherical (n = 8), ovoid (n = 2), tubular (n = 5) and early filamentous (n = 6).
The adenylate cyclase and associated proteins mentioned above, along with Hsp82p and Hsc82p, activate the cAMP pathway [ 19 ] , a pathway that acts in parallel with the MAPK pathway to promote filamentation.
HSC70 is a constituitively expressed member of the 70 kDa heat-shock protein (HSP70) family.