Words similar to hsn
Example sentences for: hsn
How can you use “hsn” in a sentence? Here are some example sentences to help you improve your vocabulary:
HsN3 is one of the seven β subunits of the 20S proteasome, which is the catalytic core of the 26S proteasome [ 22 23 24 ] . Besides its role as an indispensable component of the 20S proteasome, HsN3 and the α subunit HC9 of the 20S proteasome have been shown to interact with the viral protein Tax.
These data collectively point out the transient interaction between Smad1 and HsN3 along the assembly of HsN3 into the 20S proteasome.
When the activated BMP type I receptor was co-expressed with Smad1 and HsN3, a reduction of Smad1 level was detected and the reduction is blocked by the addition of the proteasome inhibitor lactacystin, indicating the proteasomal degradation of Smad1 induced by BMP type I receptor activation.
Second, the final maturation of the 20S proteasome resulted from the assembly of two half proteasomes into the four stacked ring structure could trap the already bound Smad1 inside the proteasome for rapid degradation or lead to the dissociation of Smad1 from mature 20S proteasome due to the inaccessibility of Smad1 binding site on the incorporated HsN3.
We have shown that the reason for Smad1 to only bind to the unprocessed form of HsN3 is not because the prosequence contains a Smad1-binding site.
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