Words similar to hsd

Example sentences for: hsd

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Although Slc5a7, Nrif-2, Srd5a1 , and Hsd17b3 are promising candidates to underlie these two QTLs, a significant number of altered genes were also identified that cannot formally be ruled out at this time, either in place of, or in addition to, these three genes.
In addition, definitive confirmation that Slc5a7, Nrif-2, Srd5a1 and Hsd17b3 (or other promising candidate genes if they arise) are involved in predisposition to physical dependence on ethanol will probably require verification using transgenics (for example, allele substitution or bacterial artificial chromosome transgenics).
A third altered candidate gene within the chromosome 13 QTL is Hsd17b3 . This gene encodes a 17β-hydroxysteroid dehydrogenase expressed primarily in testis but also in several other tissues, including brain [ 30].
Moreover, despite multiple sites of action, the drug's actions cannot be dismissed as non-specific, because 4-AP had no effects on either 3β-hydroxysteroid dehydrogenase (3β-HSD)-mediated conversion of pregnenolone to progesterone, or androgen (androstenedione, 5αDHT)-stimulated progesterone synthesis.
As discussed below, three genes for which allelic variations were detected, Srd5a1, Nrif-2 , and Hsd17b3 are thought to be particularly promising biological candidates to underlie the chromosome 13 QTL.