Words similar to hscop
Example sentences for: hscop
How can you use “hscop” in a sentence? Here are some example sentences to help you improve your vocabulary:
1) encodes a protein product that corresponds to the full-length AtCOP1, but without the ATG start codon at its 5' end [ 20 ] . Homology search against the updated public EST database with the 5' end sequence of the available partial MmCOP1 cDNA allowed the identification of human and mouse EST clones containing a predicted starting codon and a partial 5' UTR, and the subsequent construction of full-length MmCOP1 and HsCOP1 cDNAs (see Experimental procedures for details).
Because only the homologous sequences on chromosome 1 match 100% with the HsCOP1 cDNA, we conclude that the functional human COP1 gene (designated HsCOP1 ) is located on chromosome 1q24.
The full-length MmCOP1 and HsCOP1 cDNAs (GenBank accession numbers AF151110.
The genomic sequences of different COP1 orthologs were identified by BLASTn search with HsCOP1 or MmCOP1 cDNA sequence, or by tBLASTn search with HsCOP1 protein sequence in the following genomic blast sites: http://www.ncbi.nlm.nih.gov/genome/seq/HsBlast.htmlfor human genome; http://www.ncbi.nlm.nih.gov/genome/seq/MmBlast.htmlfor mouse genome; http://www.ncbi.nlm.nih.gov/PMGifs/Genomes/agambiae.htmlfor mosquito; and http://www.ncbi.nlm.nih.gov/BLAST/fugu.htmlfor fugu genome.
To reveal their evolutionary relationship, we generated a phylogenetic tree based on the amino acid sequences of the N-terminal RING finger containing fragments (all corresponding to the first 200 amino acids of HsCOP1) from representative COP1 homologues, as only partial COP1 sequences are available in the public database for some species.
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