Words similar to hrt
Example sentences for: hrt
How can you use “hrt” in a sentence? Here are some example sentences to help you improve your vocabulary:
The results of our initial analysis led to the construction of a multiple stepwise logistic regression model in which type of procedure, oophorectomy, use of HRT, frequency of intercourse prior to surgery, and preoperative expectations were used to predict the various sexual function outcome measures.
Studies in budding yeast identified SCF Cdc4p, an E3 ubiquitin ligase complex that mediates the ubiquitylation of the CDK inhibitor Sic1p [ 3 4 ] . SCF Cdc4pconsists of at least four proteins: the cullin Cdc53p, the RING domain protein Hrt1p/Rbx1p/Roc1p, the adapter protein Skp1p, and Cdc4p (reviewed in [ 1 ] ). Cdc4p contains two sequence motifs, which are conserved in a wide variety of so-called F-box proteins: C-terminal WD-repeats that are involved in binding the substrate Sic1p in a phosphorylation-dependent manner, and a central F-box [ 5 ] that interacts with Skp1p [ 6 7 ] . Cdc53p in turn binds to Skp1p and Hrt1p/Rbx1p/Roc1p, which bridges Cdc53p with the ubiquitin-conjugating enzyme Cdc34p/Ubc3p [ 6 8 9 10 11 12 ] . In vitro reconstitution demonstrated that SCF Cdc4p, Cdc34p, E1, ubiquitin, and ATP are sufficient to mediate Sic1p polyubiquitylation [ 6 7 ] .
In a recent large-scale screen with 1739 yeast proteins used as bait [ 3 ] , midasin (YLR106p) was identified in the polypeptide sets that copurified with four bait proteins, ESS1p, RPT1p, YML029p and HRT1p, that function principally in RNA metabolism and in the regulation of proteasomes (which are mostly intranuclear in yeast [ 50 ] ). However, the interpretation of these proteomic data is clouded by the fact that no protein partners were identified in the complementary experiment in which midasin was itself used as bait.
If 9 women took lifelong HRT, it would prevent one of the 9 from having a hip fracture.
The alternative explanation (referred to as "x out of 100") was worded "If 100 women just like you were to take lifelong HRT, treatment would prevent 12 of them from developing heart disease and 11 of them from developing a hip fracture.
Loading...