Example sentences for: hnt

How can you use “hnt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An earlier report demonstrated that disruption of HNT2 was tolerated by haploid yeast strains without an effect on growth and that ApppN and AppppN accumulate 30 and 3-fold, respectively on account of the hnt2 deletion [ 13 ] . Because those data were obtained by random spore analysis, we considered it important to test whether elevated dinucleoside polyphosphate levels co-segregate with hnt2 disruption in all tetrads examined and whether any other commonly used genetic markers affect dinucleoside polyphosphate levels.

  • It had been reported that Hnt2 controls ApppN levels in vivo , with a minor effect on AppppN [ 13 ] . Here we show that the ade2 mutation present in earlier experiments prevents accumulation of ApppN and AppppN and reduced the magnitude of the Hnt2 effect.

  • Among the hnt2 samples, only heat shocked samples showed evidence of ApppN levels higher than the levels in nonstressed hnt2 cells.

  • As shown in Table 6, the hnt2 samples had substantially higher ApppN levels than HNT2 samples under all conditions.

  • Loss of Hnt1 enzymatic activity also renders cells hypersensitive to mutations in the cyclin H homolog Ccl1, the MAT1 homolog Tfb3, and to Cak1, the activating kinase for Kin28, all of which lead to destabilized Kin28 complexes and a likely increase in concentration of Kin28 monomers [ 30].


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