Words similar to hnt
Example sentences for: hnt
How can you use “hnt” in a sentence? Here are some example sentences to help you improve your vocabulary:
An earlier report demonstrated that disruption of HNT2 was tolerated by haploid yeast strains without an effect on growth and that ApppN and AppppN accumulate 30 and 3-fold, respectively on account of the hnt2 deletion [ 13 ] . Because those data were obtained by random spore analysis, we considered it important to test whether elevated dinucleoside polyphosphate levels co-segregate with hnt2 disruption in all tetrads examined and whether any other commonly used genetic markers affect dinucleoside polyphosphate levels.
It had been reported that Hnt2 controls ApppN levels in vivo , with a minor effect on AppppN [ 13 ] . Here we show that the ade2 mutation present in earlier experiments prevents accumulation of ApppN and AppppN and reduced the magnitude of the Hnt2 effect.
Among the hnt2 samples, only heat shocked samples showed evidence of ApppN levels higher than the levels in nonstressed hnt2 cells.
As shown in Table 6, the hnt2 samples had substantially higher ApppN levels than HNT2 samples under all conditions.
Loss of Hnt1 enzymatic activity also renders cells hypersensitive to mutations in the cyclin H homolog Ccl1, the MAT1 homolog Tfb3, and to Cak1, the activating kinase for Kin28, all of which lead to destabilized Kin28 complexes and a likely increase in concentration of Kin28 monomers [ 30].