Words similar to hnrnpa

Example sentences for: hnrnpa

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Sequences derived from hnRNPA2/B1 sequences downstream of the site of integration also hybridized to the 1.8 kb transcript in both wild type and 1B4 homozygous mice indicating that transcription of full-length hnRNP A2/B1 transcripts is not completely disrupted by the 1B4 provirus.
Previous Northern blot analysis found high levels of a 2.3 Kb fusion transcript in 1B4 cells [ 29 ] , approximately the size expected for hnRNPA2/neo fusion transcripts terminating in the 5' LTR.
In each case, the size of the amplified product was consistent with insertion of the provirus into the hnRNPA2/B1 gene (data not shown).
Therefore, expression of the hnRNPA2/B1 gene was only reduced to about half of wild type levels, and the mutation caused no obvious phenotype in mice.
Therefore, hnRNPA2/B1-Neo transcripts are expected to encode a fusion protein consisting of the amino terminal 219 amino acids of hnRNP A2/B1 fused to amino acid 10 of the neomycin phosphotransferase (NPT) protein.