Example sentences for: hnrnp

How can you use “hnrnp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Toward this end, the present study characterised a mutation generated by insertion of the U3Neo gene trap retrovirus into an intron of the hnRNP A2/B1 gene.

  • The majority of hnRNP A2/B1-Neo fusion transcripts utilised a cryptic 3' splice site within the NPT coding sequence.

  • The gene encodes two related nuclear ribonucleoproteins, hnRNP A2 and hnRNP B1, members of a large family of RNA binding proteins found associated with mammalian heterogeneous nuclear RNA [ 33 ] .

  • Accordingly, poly(A) sites are not efficiently recognised when positioned between 5' and 3' splice sites [ 38 39 ] , and insertion of a 5' splice site into a 3' terminal exon suppresses polyadenylation [ 40 42 ] . Conversely, upstream 3' splice sites can enhance polyadenylation [ 43 44 45 ] . We find that the proximal hnRNP A2/B1 exon upstream of the provirus does not lose its identity; rather, the exon splices either to the Neo splice site or to the next hnRNP A2/B1 exon.

  • In order to determine where the provirus inserted within the hnRNP A2/B1 gene, genomic DNA flanking the 1B4 provirus was sequenced.


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