Example sentences for: hnf

How can you use “hnf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, here we have used this approach to establish that the introduction of a LacZ transgene into the Hnf3 α locus facilitates transgene expression throughout the developing gut (Fig 4).

  • The 3' arm of homology was cloned as a 4.5 kb Xho1 fragment of Hnf3α genomic DNA.

  • Rat G6pc has HNF4α consensus binding sites [ 52 ] . In HeLa cells and HepG2 hepatoma cells, PUFA down regulated G6pc, possibly via inhibition of HNF 4α promoter activity [ 52 ] . In our current mouse experiment, the transcriptional effects of LC-PUFA on G6pc may thus have been HNF4α- or PPARα mediated.

  • Importantly, this fragment extended from 5' genomic DNA into sequences encoding the untranslated 5' end of Hnf3 α mRNA.

  • Our ultimate goal is to target a number of different transgenes to the Hnf3 α locus with the aim of expressing them ectopically throughout the embryonic gut endoderm.


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