Example sentences for: hnf

How can you use “hnf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the example presented here we chose the Hnf3 α locus because Hnf3α is expressed throughout the embryonic gut endoderm of the mouse and our ultimate objective is to assess the function of transgenes expressed in this tissue [ 10, 11, 12, 13].

  • Finally the 5' arm of homology was provided by a 4.5 kb Xho I fragment of Hnf3 α genomic DNA that was introduced into a unique Pac1 site (blunt) in the preceding plasmid.

  • In contrast, we predicted that homologous recombination between the truncated Neo sequences in the targeting vector and Neo sequences within Hnf3αΔpgk-Neo ES cells would reconstitute expression of active neomycin phosphotransferase and so confer resistance to G418.

  • In addition, mice lacking a single Hnf3 α allele have no observable phenotype, so that introduction of transgenes into this locus will not inherently affect embryonic development [ 14, 15].

  • It is likely that this intron or other untranslated sequences contain regulatory elements that specifically direct expression of Hnf3αLacZ in the floorplate of the neural tube and notochord [ 21].


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