Words similar to hne

Example sentences for: hne

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15d-PGJ 2 , 15-deoxy-delta 12, 14-Prostaglandin J 2 ; ERK, Extracellular signal-Regulated Kinase; 4-HNE, 4-hydroxynonenal, MAP kinases, Mitogen-Activated Protein kinases; MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide); PBS, phosphate-buffered saline; PPARs, peroxisome proliferator-activated receptors; RPE, retinal pigment epithelium.
Even though ocular tissues, including the retina, contain glutathione S-transferases that can actively detoxify 4-HNE [ 35 67 ] , adverse events may occur if aging or pathological conditions hinder this normal defense from functioning properly.
No particular protein was identified as a specific target for 4-HNE adduct formation in these studies.
first reported oxidative stress caused by t-butylhydroperoxide or iron/ascorbate could lead to 4-HNE protein adducts in hepatocytes [ 62 ] . Further studies by these researchers attempted to identify the common epitope recognized by the 4-HNE antibodies.
Subsequent experiments with immunofluorescent staining indicated that 1.5 mM H 2 O 2 treatment of ARPE-19 cells for 4 hours led to the formation of 4-HNE protein adducts both in the cytoplasm and nucleus, presumably as a result of lipid-peroxidation (Fig.