Words similar to hne

Example sentences for: hne

How can you use “hne” in a sentence? Here are some example sentences to help you improve your vocabulary:

ERK activation and 4-HNE protein adducts formation as a result of oxidative stress
It warrants further studies to identify those proteins species that are modified by 4-HNE.
No particular protein was identified as a specific target for 4-HNE adduct formation in these studies.
An accumulation of 4-HNE-conjugated protein has been detected in lesions of aging-related diseases, including Parkinson's disease [ 53 ] and Alzheimer's disease [ 54 ] . It also accumulates in the affected neuronal tissues of experimental animals experiencing brain ischemia [ 55 56 ] and traumatic spinal cord injury [ 57 ] . 4-HNE can impair synaptosomal membrane proteins, glutamate transport and importantly, mitochondrial functions [ 58 59 ] . Evidence indicates that 4-HNE increases neuronal susceptibility to oxidative stress [ 60 ] and serves as a mediator of oxidative stress that leads to neuronal apoptosis [ 61 ] . As indicated in the Introduction, 4-HNE has been implicated in some ocular pathological conditions [ 19 20 ] .
However, no specific protein was positively identified [ 63 ] . More recently, the formation of 4-HNE protein adducts was also demonstrated by Western blot analysis from the heart [ 64 ] , the liver [ 65 ] and the kidney [ 66 ] under oxidative stress.