Words similar to hne

Example sentences for: hne

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This study demonstrates that oxidative stress induced by H 2 O 2 could lead to RPE cell death, which is preceded by distinct morphological changes, ERK activation and 4-HNE protein adduct formation.
Various protein bands on Western blots were positive for anti-HNE antibody reactivity, further intensified as a result of H 2 O 2 treatment (Fig 3C).
However, no specific protein was positively identified [ 63 ] . More recently, the formation of 4-HNE protein adducts was also demonstrated by Western blot analysis from the heart [ 64 ] , the liver [ 65 ] and the kidney [ 66 ] under oxidative stress.
For example, levels of 4-HNE increased significantly in the vitreous of patients with proliferative vitreoretinopathy compared with controls [ 17 ] . Further, 4-HNE forms a stable adduct with rhodopsin in the photoreceptor, which may interfere with its functions [ 18 ] . 4-HNE even causes cataracts in cultured rat lens [ 19 20 ] . Whether oxidative stress on RPE can cause accumulation of cellular HNE-protein adducts remains unknown.
ERK activation and 4-HNE protein adducts formation as a result of oxidative stress