Words similar to hmgcoa
Example sentences for: hmgcoa
How can you use “hmgcoa” in a sentence? Here are some example sentences to help you improve your vocabulary:
Statins block HMGCoA reductase generation of mevalonate from 3-hydroxy-methyl-glutarate (see Figure 7).
To test whether statin-activated shedding might be attributable to a metabolite downstream of HMGCoA reductase, cells were treated with 1 μM simvastatin, 5 μM FTI-1, and a series of concentrations of mevalonic acid.
Since FTI-1 acts downstream of HMGCoA reductase, the stimulatory effect of FTI-1 on sAPP α shedding would not be predicted to be modified by mevalonate supplementation.
Reports from retrospective analyses suggest that the statin class of cholesterol-lowering HMGCoA reductase inhibitors may lower the risk for Alzheimer disease by as much as 70% [8,9,10,11].