Words similar to hmgb

Example sentences for: hmgb

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For example, RAG1 has been reported to interact with the tandem HMG-boxes of HMGB1 or HMGB2 [ 6 ] . Where it has been studied, HMG-boxes have been shown to be structurally related, forming three α-helices in a characteristic L-shaped structure [ 3 7 ] . The distortion of DNA by the HMG-box is primarily mediated through contacts with the minor groove of the DNA helix, potentially allowing simultaneous binding of other transcriptional regulators to the DNA [ 8 9 ] . The HMG-box family has often been subdivided based on DNA binding properties.
All members of the HMG-box family possess a 70-80 amino acid DNA-binding domain (the HMG-box) related to a motif originally identified in HMGB1 [ 5 ] . The HMG-box may also be involved in protein-protein interactions.
1), LOC244579 mRNA (XM_146430), SOX-4 protein (NP_033264), SOX-17 protein (NP_035571), LEF-1 protein NP_034833), HMGB1 protein (CAA56631), upstream binding factor 1 (UBF-1) protein (NP_035681).
UBF-1 specifically binds the ribosomal RNA gene promoter, although no particular recognition sequence can be identified [ 22 ] . HMGB1 and UBF-1 contain multiple HMG-box motifs, although only one is shown (indicated by decimal in Fig.
Murine HMGB1 and yeast NHP6A bind DNA in a sequence-independent fashion.