Words similar to hmg-box

Example sentences for: hmg-box

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There is also clear similarity between these pufferfish protein sequences and the TOX subfamily in regions outside of the putative NLS and HMG-box.
For example, RAG1 has been reported to interact with the tandem HMG-boxes of HMGB1 or HMGB2 [ 6 ] . Where it has been studied, HMG-boxes have been shown to be structurally related, forming three α-helices in a characteristic L-shaped structure [ 3 7 ] . The distortion of DNA by the HMG-box is primarily mediated through contacts with the minor groove of the DNA helix, potentially allowing simultaneous binding of other transcriptional regulators to the DNA [ 8 9 ] . The HMG-box family has often been subdivided based on DNA binding properties.
Outside of the HMG-box and NLS, the murine and human homologues of the three additional pairs of proteins are highly conserved, as we reported for TOX and KIAA0808 [ 15 ] . LCP1 and KIAA0737 proteins are approximately 94% identical, while LOC241768 and C20ORF100 share 85% identity.
Interestingly, the position of the intron/exon boundary encoding the HMG-box is precisely conserved among all family members in mouse and human (Fig.
This mosquito HMG-box is approximately 90% identical to that found in the mammalian TOX subfamily, despite the considerable evolutionary history separating the two.