Words similar to hmg-box

Example sentences for: hmg-box

How can you use “hmg-box” in a sentence? Here are some example sentences to help you improve your vocabulary:

UBF-1 specifically binds the ribosomal RNA gene promoter, although no particular recognition sequence can be identified [ 22 ] . HMGB1 and UBF-1 contain multiple HMG-box motifs, although only one is shown (indicated by decimal in Fig.
Unlike other sequence-independent HMG-box proteins, which show ubiquitous tissue expression, we have previously shown that TOX has a highly regulated tissue and developmental expression profile.
For example, RAG1 has been reported to interact with the tandem HMG-boxes of HMGB1 or HMGB2 [ 6 ] . Where it has been studied, HMG-boxes have been shown to be structurally related, forming three α-helices in a characteristic L-shaped structure [ 3 7 ] . The distortion of DNA by the HMG-box is primarily mediated through contacts with the minor groove of the DNA helix, potentially allowing simultaneous binding of other transcriptional regulators to the DNA [ 8 9 ] . The HMG-box family has often been subdivided based on DNA binding properties.
Interestingly, the position of the intron/exon boundary encoding the HMG-box is precisely conserved among all family members in mouse and human (Fig.
In this study, we introduce a subfamily of three additional mammalian proteins, which share a common HMG-box domain with TOX.