Words similar to hmg-box
Example sentences for: hmg-box
How can you use “hmg-box” in a sentence? Here are some example sentences to help you improve your vocabulary:
Figure 1shows an alignment of the HMG-box region of TOX with HMG-box motifs found in seven other proteins representing the two major subfamilies of HMG-box proteins.
In this study, we introduce a subfamily of three additional mammalian proteins, which share a common HMG-box domain with TOX.
Several other HMG-box proteins also play important roles in lymphocyte development [ 17 ] . Mice doubly deficient in lymphocyte enhancement factor-1 (LEF-1) and T cell factor-1 (TCF-1) have a complete block in development of T cells [ 18 19 ] , while deficiency of SRY-box containing protein 4 (SOX-4) in mice results in a lack of pro-B cell expansion and mild perturbation of thymocyte development [ 20 ] . Unlike these HMG-box proteins, however, we find that the HMG-box of TOX is more closely related to the DNA binding domain of sequence-independent HMG-box proteins.
TOX is a member of a four-protein subfamily with nearly identical HMG-box sequences
The HMG-box splits TOX family proteins into two domains of approximately 200-300 amino acids.