Words similar to hmga

Example sentences for: hmga

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Many of these structural changes are mediated by high mobility group (HMG) proteins, a diverse superfamily of non-histone chromosomal proteins that were originally classified by their electrophoretic mobility [ 1 ] . HMG proteins contain DNA-binding domains that allow them to produce specific changes in target DNA structure [ 2 3 ] . Three structurally distinct classes of HMG proteins have been defined; the HMG-nucleosomal binding family, the HMG-AT-hook family, and the HMG-box family (whose canonical members are referred to as HMGN, HMGA and HMGB respectively) [ 4 ] . In addition, a large number of proteins have been found that contain HMG protein related motifs.